Check · Flag · Dose · You sign

Clinical decision support software that checks drug interactions before you sign

Checks every prescription for interactions, contraindications, and renal or hepatic dosing in one card. Decision-support for licensed clinicians. You make the call and sign off.

The Monograph Desk

Ready to check

Drug / scenario + Second drug / context

Press Run check to see the interaction, contraindication, and dosing decision-support card for this scenario.

Not in this sample

This on-page demo only ships with five illustrative scenarios and never invents clinical output, so it will not fake a card for this pair.

The full Prescriber.io desk checks any regimen against interactions, contraindications, and renal or hepatic dosing, with cited sources for you to verify.

Illustrative sample · decision-support only · verify against official sources

Interaction

Contraindication / allergy check

Dosing guidance (renal / hepatic)

Guideline-based alternatives

Sources

Illustrative sample · not real clinical advice · you verify and decide

Clinician-in-the-loop

Checked in · you review & sign

Decision support for licensed clinicians. Prescriber.io does not diagnose or prescribe and is not a substitute for professional clinical judgment.

Clinician-in-the-loop Sources cited No PHI required

In short

Prescriber.io is clinical decision support software for licensed US clinicians. Enter a drug, a drug pair, or a prescribing scenario and it returns a single card: drug-drug interactions flagged with the mechanism, contraindications and allergies surfaced in plain language, renal and hepatic dose adjustments suggested, and guideline-based alternatives, each with its source cited. It is decision support rather than autonomous prescribing, so the clinician reviews every flag, verifies it against the current labeling, and signs. Plans run $29 to $59 per clinician per month billed annually, with Enterprise quoted on request.

Last updated July 2026

Built for the clinicians who prescribe

Physicians Nurse practitioners Physician associates Clinical pharmacists

No autonomous prescribing

Why clinicians use it

One check for the whole prescription

Existing references make you run separate lookups. Prescriber.io brings the interaction, contraindication, dose-adjustment, and alternatives check into a single card at the point of care. You stay the decision-maker on every script.

Catch interactions before you sign

Every prescription gets a structured second read for drug-drug interactions, so a missed CYP interaction is flagged while you can still act on it.

Contraindications surfaced early

Allergies and contraindications buried in the picture are surfaced in plain language, so the blocker shows up before the script does, not after.

Renal and hepatic dosing in one place

Dose adjustments for reduced renal or hepatic function arrive alongside the interaction check, as decision-support you confirm and apply.

Less tab-hopping across references

Interaction, contraindication, dosing, and guideline alternatives in one card, so you stop stitching together four separate lookups at the point of care.

How it works

Enter the scenario, read the card, then you decide and sign

The assistant checks the prescription and hands you a structured decision-support card. Nothing is prescribed until you, the licensed clinician, review and sign off.

01 / ENTER

Enter the drug or scenario

Type a drug and a second drug, or pick a scenario. The assistant pulls the interaction, contraindication, and dosing checks together.

02 / CHECK

Interactions and contraindications flagged

Drug-drug interactions, allergies, and contraindications are surfaced in plain language with the mechanism, not just a code.

03 / DOSE

Renal and hepatic dosing surfaced

Dose adjustments for reduced renal or hepatic function arrive alongside, with guideline-based alternatives and cited sources.

04 / REVIEW & SIGN

You verify and sign

You confirm against official sources, choose, and sign off. The card supports the decision; it never makes it for you.

See how clinical decision support works

The decision-support card

Interaction, contraindication, dosing, and your sign-off

The assistant hands you one structured card with the interaction, the contraindication check, the dose adjustment, and guideline-based alternatives, with cited sources. You verify and decide. The samples here are illustrative, not real clinical advice.

Drug-drug interactions flagged in plain language with the mechanism
Contraindications and allergies surfaced before you sign
Renal and hepatic dose adjustments alongside the interaction check
Guideline-based alternatives with cited sources, you verify and choose

Simvastatin + clarithromycin Avoid

Decision-support · illustrative

CYP3A4 inhibition raises simvastatin exposure and myopathy risk. Suspend the statin or switch to one not dependent on CYP3A4.

Sample · verify against official sources You verify & sign

Warfarin + clarithromycin Caution

Decision-support · illustrative

Reduced warfarin clearance raises INR and bleeding risk. Consider holding or reducing the dose and recheck INR in 3 to 5 days.

Sample · verify against official sources You verify & sign

Metformin in CKD Adjust dose

Decision-support · illustrative

eGFR 30 to 45: cap the daily dose and avoid initiation; reassess at each renal change.

Sample · verify against official sources You verify & sign

What it checks

Interactions, contraindications, and dosing, one card

Interactions

Drug-drug interactions flagged with the mechanism and plain-language risk, so the check is actionable at the point of care.

Explore Interactions

Contraindications

Allergies and contraindications surfaced from the scenario, so the blocker shows up before the prescription does.

Explore Contraindications

Renal & hepatic dosing

Dose adjustments for reduced renal or hepatic function, with guideline-based alternatives and cited sources.

Explore Renal & hepatic dosing

Built for prescribers

However you prescribe, Prescriber.io fits the point of care

From solo prescribers to group practices, clinics, and health-system pharmacy teams, the assistant supports the way you already check and decide.

Drug interaction checker

One integrated check for interactions before you sign, not five separate lookups.

Learn more

Drug dosing calculator

Dosing guidance in context, with adjustments surfaced for review.

Learn more

Prescribing software

Safety checks built into the moment of prescribing, not bolted on after.

Learn more

Drug contraindication checker

Surface contraindications hiding in the chart before they become harm.

Learn more

Renal dosing calculator

Renal dose adjustments surfaced against kidney function, with sources.

Learn more

Point-of-care clinical decision support

Answers in the room, in one card, while the decision is live.

Learn more

See every way clinicians prescribe with Prescriber.io

Scope of the tool

What the assistant does, and where it stops

One card instead of separate lookups

Enter the drugs or the scenario once and the interaction check, the contraindication check, and the dose adjustment come back on a single structured card, rather than requiring a separate lookup in a separate reference for each of the three.

Mechanism and source, not just a flag

Each item is written in plain language with the mechanism behind it and a severity level, and guideline-based alternatives carry cited sources. The citation is there so you can open it and confirm the underlying reference yourself.

It does not prescribe

The assistant produces decision support and nothing else. It writes no prescription, sends nothing to a pharmacy, and takes no action on a patient record. Every output is a prompt for the licensed clinician to verify and act on, or to disregard.

Decision support only. Final prescribing decisions always rest with the licensed clinician, who verifies against official sources.

Prescriber decision support pricing

Per-clinician plans that scale with your practice

Every plan is paid and includes interaction, contraindication, and dosing decision-support with cited sources. Prices in USD. Choose a plan to get started.

Solo

Individual prescriber

$39/clinician/mo

Interaction and contraindication checks
Renal and hepatic dosing guidance
Guideline-based alternatives
Cited sources on every flag
Single seat

Practice

Small group or clinic

$29/clinician/mo

Team rate, minimum seats

Everything in Solo
Shared formulary preferences
Team seats, billed annually
Priority support
Most popular with clinics

Clinic+

Larger practices and pharmacies

$59/clinician/mo

Everything in Practice
Polypharmacy and reconciliation review
SSO for your team
Custom onboarding

Prices in USD, per clinician. Need a health-system plan? See full decision support pricing.

Before you start

The questions clinicians ask first

No. Prescriber.io is decision-support only. It checks for interactions, contraindications, and dosing and suggests options. You, the licensed clinician, review every suggestion, verify against official sources, and sign off. It is not a substitute for professional judgment.

We make no medical-device or regulatory-clearance claims. Prescriber.io is a clinical reference and decision-support tool to support your judgment, not a substitute for it.

It is built on clinical pharmacology references and cites its sources so you can confirm. Always verify against official sources before prescribing. The tool supports, never replaces, your clinical judgment. We do not publish accuracy figures in our marketing, by design.

Licensed clinicians, physicians, NPs, PAs, and clinical pharmacists. It is not for patients or consumers.

The product is built so you never need to enter PHI to get an answer. You decide what context to type, and a BAA is discussed at onboarding for Enterprise. We hold no HIPAA certification and do not claim one.

No. It is a decision-support layer alongside your workflow. You still prescribe and sign in your own system.

Clinical decision support systems match the medication and patient picture in front of you against clinical knowledge, then surface the result at the point of care: interaction flags with the mechanism, contraindication and allergy warnings, dose adjustments for reduced renal or hepatic function, and guideline reminders. They inform the prescriber. The clinician still reviews each flag and signs.

Drug interaction checkers, renal dosing calculators, the allergy and contraindication alerts built into an EHR, and clinical reference tools such as UpToDate, Lexidrug, Micromedex and Prescriber.io are all clinical decision support software. Prescriber.io is the kind that folds the interaction check, the contraindication check, the renal or hepatic dose adjustment and guideline alternatives into one card with cited sources.

Prescriber.io is $39 per clinician per month on Solo, $29 per clinician per month on the Practice team plan, and $59 on Clinic+, each billed annually in USD, with Enterprise quoted on request. For comparison, individual subscriptions to the large clinical references commonly run from roughly $180 to $580 a year, while institutional products such as Micromedex are quoted rather than listed.

Read every clinical decision support question

Catch the interaction before you sign the prescription

Check every prescription for interactions, contraindications, and dosing in one card. Decision-support for licensed clinicians. You make the call.

See pricing

Prescriber.io is a decision-support tool for licensed clinicians. It does not diagnose or prescribe and is not a substitute for professional clinical judgment. Verify against official sources. Final prescribing decisions always rest with the licensed clinician.